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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UHRF2
All Species:
13.64
Human Site:
Y386
Identified Species:
27.27
UniProt:
Q96PU4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU4
NP_690856.1
802
89985
Y386
D
K
V
P
E
E
E
Y
W
Y
C
P
S
C
K
Chimpanzee
Pan troglodytes
XP_001142916
802
89978
Y386
D
K
V
P
E
E
E
Y
W
Y
C
P
S
C
K
Rhesus Macaque
Macaca mulatta
XP_001082893
795
89906
E359
S
S
V
P
S
E
D
E
W
Y
C
P
E
C
R
Dog
Lupus familis
XP_851749
803
89759
Y387
D
K
V
P
E
E
E
Y
W
Y
C
P
S
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMI3
803
90087
Y387
D
K
V
P
E
E
E
Y
W
Y
C
P
S
C
K
Rat
Rattus norvegicus
Q7TPK1
774
87430
E354
T
C
V
P
P
E
P
E
W
Y
C
P
S
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507628
851
95788
D425
S
K
I
P
E
D
E
D
W
Y
C
P
S
C
K
Chicken
Gallus gallus
XP_418269
760
84868
D342
S
S
I
P
D
D
E
D
W
Y
C
P
E
C
R
Frog
Xenopus laevis
NP_001091384
845
95104
D382
E
K
I
P
E
D
E
D
W
Y
C
P
S
C
K
Zebra Danio
Brachydanio rerio
NP_998242
775
87072
D354
T
T
I
P
D
D
E
D
W
Y
C
P
D
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120707
568
64844
K171
C
L
D
N
P
R
K
K
C
R
E
C
G
C
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791602
653
73619
K256
K
A
S
K
K
K
S
K
M
A
S
A
T
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54.3
91.4
N.A.
90.7
51.8
N.A.
65.4
50.7
64.5
52.8
N.A.
N.A.
40.6
N.A.
39.5
Protein Similarity:
100
100
70.6
94.5
N.A.
94.8
67.5
N.A.
77.3
66.3
77.4
70.5
N.A.
N.A.
53.4
N.A.
55.1
P-Site Identity:
100
100
53.3
100
N.A.
100
60
N.A.
73.3
46.6
73.3
46.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
66.6
100
N.A.
100
66.6
N.A.
86.6
73.3
93.3
73.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
9
0
9
0
0
0
% A
% Cys:
9
9
0
0
0
0
0
0
9
0
84
9
0
92
0
% C
% Asp:
34
0
9
0
17
34
9
34
0
0
0
0
9
0
0
% D
% Glu:
9
0
0
0
50
50
67
17
0
0
9
0
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
50
0
9
9
9
9
17
0
0
0
0
0
0
50
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
84
17
0
9
0
0
0
0
84
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
42
% R
% Ser:
25
17
9
0
9
0
9
0
0
0
9
0
59
9
0
% S
% Thr:
17
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% T
% Val:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
84
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _